In this paper, we use evidence from our earlier review of surgical randomised controlled trials with a placebo arm to show that blinding in trials of interventional procedures is feasible.We give examples of ingenious strategies that have been used to simulate the active procedure and to Corner Chair make the placebo control indistinguishable from

Non-technical loss (NTL) detection is a persistent challenge for Distribution System Operators.Data-driven solutions have been widely used nowadays to analyze customers’ energy consumption and to identify suspicious fraud patterns for a posterior on-field inspection.However, the usage of such techniques, in particular the current deep learni

ABSTRACT The high global burden of cryptococcosis has made development of a protective vaccine a public health priority.We previously demonstrated that a vaccine composed of recombinant Cryptococcus neoformans chitin deacetylase 2 (Cda2) delivered in glucan particles (GPs) protects BALB/c and C57BL/6 mice from an otherwise lethal challenge with a h

Mesencephalic dopaminergic neurons were suggested to be a critical physiopathology substrate for addiction Body lotion disorders.Among neuroadaptive processes to addictive drugs, structural plasticity has attracted attention.While structural plasticity occurs at both pre- and post-synaptic levels in the mesolimbic dopaminergic system, the present r